A team from Fred Hutchinson Cancer Research Center in Seattle (United States) has achieved isolate and map the CV30 antibody, which directly attacks SARS-CoV-2 with a 530 times higher efficiency than other antibodies.
The substance was isolated from a sample of a Washington patient taken during the early days of the pandemic. The CV30 is able to neutralize the spikes of the virus that are on the surface, managing to break them.
This antibody, of which Drs. Leo Stamatatos, Andrew McGuire and Marie Pancera have managed to draw a molecular map, is 530 times more effective against the coronavirus than the other substances investigated. Work has been published in the journal ‘Nature Communications’.
How do you attack the coronavirus?
CV30 attacks the coronavirus in two ways. “One of the mechanisms is that overlaps the target site of the virus in human cells, and the other is that it induces removal or dissociation of part of the spike of the rest, “explains Dr. Marie Pancera.
The antibody also causes section S1 to cut, which plays a crucial role when the coronavirus enters the cells of the infected person. Although it’s still too early to tell, scientists have high hopes that this new find will be tremendously beneficial when researching new treatments and vaccines against Covid-19.