A group of Russian specialists analyzed the medical records of 110 patients who died from pneumonia caused by SARS-Cov-2 and identified factors that increase the risk of severe course. Hypertensive patients and diabetics are in the number one risk group, but no connection between the severe course of COVID-19 and pregnancy and liver cirrhosis has been identified.
In a retrospective study, published in the medical journal “Attending Physician” analyzed the stories of 55 men and 55 women who died from coronavirus pneumonia. The average age is 75. Doctors and pathologists assessed the presence of risk factors for severe disease, somatic pathology, and computed tomography of the lungs.
The most important risk factor was essential arterial hypertension (hypertension) – 93.6% of the deaths (103 patients) suffered from this chronic disease. Most of the patients were in the age group over 65 years old – 81.8% (90 patients). Diabetes mellitus was noted in 66.3% of deaths (73 patients), chronic heart failure – in 46.3% of cases (51 patients). P
“A severe course with a fatal outcome is most often recorded in people of the older age group with diseases of the cardiovascular system, cerebrovascular pathology and malignant neoplasms. Even patients in young and older age groups had risk factors for a poor prognosis, ”the study authors said.
At the same time, such risk factors as liver cirrhosis, acute coronary syndrome, therapy with steroid or biological drugs, pregnancy, in the observed cases, were extremely rare.
Experts also analyzed the symptoms, which may indicate the development of complications with COVID-19. According to the study, the most adverse symptoms – body temperature above 38 ° C, shortness of breath and weakness – occur primarily six days after hospitalization, while other symptoms appear mainly 3-5 days before the patient is admitted. in hospital.
“Patients who have risk factors such as age over 65 years, arterial hypertension and heart failure, combined with symptoms such as fever above 38 ° C, shortness of breath and weakness, require immediate hospitalization, regardless of the level of hypoxemia and changes according to computed tomography data, for further observation and treatment in connection with the high probability of death, ”the authors of the study said.