A new variant of the coronavirus was discovered in Angola, called A.VOI.V2, with more mutations than any other variant known to date
Variants of the South African coronavirus are already well known, and this mutation makes it more contagious and the vaccine is less effective. Now, a new variant has been discovered in Angola, although its characteristics are still unknown.
In Angola, the government has taken strict measures to test and quarantine air travelers with symptoms of infection. This allows experts to find travelers from Tanzania who carry a hitherto unknown variant, A.VOI.V2, with more mutations in the genome than any other strain of the virus previously discovered.
Types of coronavirus vaccines
According to a research team led by infectious disease researcher Tulio de Oliveira, the genome of this variant can contain up to 40 mutations. Advance publication on MedRxiv. “There is no doubt that this is a worrying change,” is a statement by the Director of the Pan-African Health Bureau. African Center for Disease Control and Prevention, John Nkengasong.
The A.VOI.V2 variant is more infectious than other forms. To some extent, does it produce severe symptoms, or whether it can be determined whether the vaccine can prevent its infection, because there is no time to fully study it. It is unclear whether A.VOI.V2 originated in Tanzania, or whether it was picked up by travellers at other borders on the way to Angola.
As we all know, in any case, the emergence of new variants seems to run counter to the prevailing view of the slow development of SARS-CoV-2 coronavirus. According to the African Centers for Disease Control and Prevention, countries near Tanzania have implemented surveillance systems.
The publication states that the mutation of the spike protein that the virus enters into the cell includes three protein substitutions at the receptor binding site, five substitutions and three deletions at the N-terminal domain, and adjacent to the receptor cleavage site. The two replacements.
Shockingly, some of these mutations are also present in other potentially dangerous variants and continue to spread due to positive selection because they make the virus more infectious.
The highly contagious B.1.1.7 variant was first discovered in the UK and has been found in 18 countries, while the B.22.214.171.124 variant of South Africa was found in another 18 countries. More than 40 million tests have been conducted in Africa. However, many cases are likely to go undetected and underreported.