A group of researchers from the Karolinska Institute in Sweden has discovered that some nanoantibodies from alpacas can help fight coronavirus infection in humans by blocking the entry of SARS-CoV-2 into cells.
The authors of this study believe that this discovery may lead to the creation of a antiviral treatment against COVID-19, which has already caused the death of more than 880,000 people, according to the media SDPnoticias.com, which echoes an article published in the magazine Nature.
Last February, these scientists injected one of these animals with the spike used by the coronavirus to enter the cells and, after 60 days, they verified that the blood of the alpaca had gotten an immune response against the external element.
Then, adapted the nanoantibody to humans, for which they cloned it and enriched it in a laboratory.
After this process, they found that this antibody neutralizes the virus by adhering to the ACE2 receptor, which is used by SARS-CoV-2 to infect human cells, thereby infection is prevented.
“We hope that our findings may contribute to the improvement of the pandemic of Covid-19 by promoting a more careful examination of this nanoantibody as a therapeutic candidate against this viral infection ”, has desired the lead author of the study, Gerald McInerney.