In recent days, people have been very concerned Blood clot, Especially after hearing the alarm Germany About people who are suffering Thrombosis After vaccination with AstraZeneca, a blood clot in the brain vein-a blood clot in the brain appears. Other European countries have expressed concern that the risk of pulmonary embolism and deep vein thrombosis after vaccination may increase.
despite this, AstraZeneca pointed out that there is currently no evidence The recorded episodes were related to the vaccine, and the number of blood clots reported after the vaccination did not exceed normal conditions.
Coagulation is an extremely important function in the human body and helps prevent Excessive bleeding When our skin, internal organs or blood vessels are damaged, whether inside or outside the body.
However, although this may be a normal and essential process, if a blood clot breaks away from where it formed, May be dangerous, Especially when it stays in an organ or artery that is too narrow. This is the so-called embolus, which can block the essential arterial blood flow to vital organs and may cause pulmonary embolism (blood clot in the lungs), ischemic stroke (blood clot in the brain) or heart attack. It can also block a vein, such as a deep vein thrombosis in the leg, called a thrombus.
Have Many factors This increases the chance of a person forming a blood clot. We will focus on five:
Obese people have More than twice as likely Compared with people of normal weight, there is a risk of thrombosis (blood clots in the legs). This is because obesity causes chronic inflammation and reduces fibrinolysis (the ability to break down blood clots).
This Chronic inflammation It also occurs due to a decrease in nitric oxide in the body. Nitric oxide is a molecule that protects the special endothelium (the lining of blood vessels) and prevents cells from attaching to the surface of the endothelium. Even at a very young age, obese people have much lower levels of nitric oxide.
The reduced level of nitric oxide in obese people increases the incidence of obesity. Damage to the lining of blood vessels, Which in turn increases the risk of blood clot formation.
Smoking increases the risk of blood clots Up to three times.
Just like obesity, smoking Reduce the level of nitric oxide in the body And help the blood stick together to form blood clots. The level of fibrinogen in the blood of smokers is an important part of coagulation, and the significant increase in fibrinogen levels is part of the reason.
This Chemicals in cigarettes They also make platelets stick together. These factors add up to thicken the blood, make it difficult for the heart to pump into the body, and damage the lining of blood vessels.
long trip aircraft Ø be fixed Long-term use after major surgery may increase the risk of blood clots in the form of deep vein thrombosis (DVT), that is, thrombosis in the legs. The typical incidence of this type of thrombosis is one per thousand, but in the case of flight time of more than three hours, multiply by three.
what Not much blood flowCells and proteins in the blood settle and form clumps. When the person moves again, if these clots are not removed, they will pass through the body and block the blood vessels. Higher body mass index, age and smoking increase the risk of deep vein thrombosis due to insufficient exercise or flying.
As many as a quarter of people have suffered severe trauma, resulting in damage to their blood vessels-for example, if Fractured bone Large-formation of blood clots. In these cases, the formation of a clot is not only related to the damage of the blood vessel itself, but also to bed rest, and bed rest is usually prolonged and is related to treatment and rehabilitation.
Also, cancer patients have Five to seven times more likely Formation of blood clots. This is because certain cancers produce more and more clotting factors. Cancer can also damage healthy tissues, causing them to swell and coagulate.